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Conjugation of the ubiquitin activating enzyme UBE1 with the ubiquitin-like modifier FAT10 targets it for proteasomal degradation.

机译：遍在蛋白激活酶UBE1与泛素样修饰物FaT10的缀合使其靶向蛋白酶体降解。

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Johanna Bialas; Marcus Groettrup; Annette Aichem;
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1. Parkin is an E3 ligase for the ubiquitin-like modifier FAT10, which inhibits Parkin activation and mitophagy [J] . Nicola D. Roverato, Carolin Sailer, Nicola Catone, Cell Reports . 2021,第11期

机译：Parkin是泛素样改性剂FAT10的E3连接酶，其抑制Parkin活化和MINOCHAGY
2. The ubiquitin-like modifier FAT10 is required for normal IFN-gamma production by activated CD8(+) T cells [J] . Mah Mei Min, Basler Michael, Groettrup Marcus Molecular Immunology . 2019,第期

机译：通过活化的CD8（+）T细胞，正常IFN-Gamma生产需要泛素样改性剂FAT10
3. The ubiquitin-like modifier FAT10 interferes with SUMO activation [J] . Annette Aichem, Carolin Sailer, Stella Ryu, Nature Communications . 2019,第1期

机译：泛素状的改性剂FAT10干扰SUMO激活
4. System-wide Analysis of SUMOylation Dynamics in Response to Replication Stress Reveals Novel Small Ubiquitin-like Modifier Target Proteins and Acceptor Lysines Relevant for Genome Stability [C] . Zhenyu Xiao, Jer-Gung Chang, Ivo A. Hendriks, ASMS Conference on Mass Spectrometry and Allied Topics . 2015

机译：响应于复制应力的Sumoylation Dynamics的系统范围分析揭示了新的小泛素样改性剂靶蛋白和受体赖氨酸，与基因组稳定性相关
5. Targeting Human Ubiquitin Activating Enzyme UBE1 with Rationally Designed Copper-Based Inhibitors and the Application of a Fluorescent Chemosensor to the Development of an Assay for Adenylating Enzyme Activity. [D] . Qureshi, Harris Iqbal. 2015

机译：针对人类的泛素激活酶UBE1与合理设计的基于铜的抑制剂和荧光化学传感器在腺苷酸化酶活性测定方法开发中的应用。
6. Conjugation of the Ubiquitin Activating Enzyme UBE1 with the Ubiquitin-Like Modifier FAT10 Targets It for Proteasomal Degradation [O] . Johanna Bialas, Marcus Groettrup, Annette Aichem -1

机译：泛素激活酶UBE1与泛素类似物修饰剂FAT10的结合将其靶向于蛋白酶体降解。
7. Mechanistic Studies on Activation of Ubiquitin and Di-ubiquitin-like Protein, FAT10, by Ubiquitin-like Modifier Activating Enzyme 6, Uba6 [O] . James M. Gavin, Jesse J. Chen, Hua Liao, 2012

机译：泛素和二 - 遍染素样蛋白，FAT10，泛素状改性剂活化酶6，UBA6的机械研究
8. UBCH8 Ubiquitin E2 Enzyme is Also the E2 Enzyme for ISG15, an Interferon Alpha/Beta Induced Ubiquitin-Like Protein. [R] . Krug, R. M., Zhao, C., Hulbregtse, J. 2004

机译：UBCH8泛素E2酶也是IsG15的E2酶，IsG15是一种干扰素α/β诱导的泛素样蛋白。

Conjugation of the ubiquitin activating enzyme UBE1 with the ubiquitin-like modifier FAT10 targets it for proteasomal degradation.

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